Southwest® flights from Knoxville to Des Moines

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Low fares from Knoxville to Des Moines

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Low fares from Knoxville to Des Moines

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    • *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Mc Ghee Tyson Airport
    Arriving at:
    Des Moines Airport
    Distance:
    654 miles

    Questions we hear the most

    There are 25 weekly flights from Knoxville to Des Moines on Southwest Airlines.
    To find the lowest fares by day and time to fly Knoxville to Des Moines with Southwest, check out our Low Fare Calendar.
    You can rent a car at Des Moines Airport book yours with your flight.
    Yes! Flights from Knoxville to Des Moines—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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