Southwest® flights from Knoxville to Fresno from $356
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1 Passenger
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today
Low fares from Knoxville to Fresno
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$
Knoxville (TYS)to
Fresno (FAT)
Depart: 11/17/2026
One-way
Basic
From
$187
Low fares from Knoxville to Fresno
$
Knoxville (TYS)to
Fresno (FAT)
Depart: 07/31/2026
One-way
Basic
From
$356
Seen: 1 hour ago
Knoxville (TYS)to
Fresno (FAT)
Depart: 07/31/2026
One-way
Choice
From
$400
Seen: 1 hour ago
Knoxville (TYS)to
Fresno (FAT)
Depart: 07/31/2026
One-way
Choice Preferred
From
$480
Seen: 1 hour ago
Knoxville (TYS)to
Fresno (FAT)
Depart: 07/31/2026
One-way
Choice Extra
From
$540
Seen: 1 hour ago
Explore flights from Knoxville to Fresno
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Flight Details
Departing from:
Mc Ghee Tyson Airport
Arriving at:
Fresno Yosemite International Airport
Distance:
1984 miles
Route Information
28† Weekly flights
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
There are 28 weekly flights from Knoxville to Fresno on Southwest Airlines.
To find the lowest fares by day and time to fly Knoxville to Fresno with Southwest, check out our Low Fare Calendar.
You can rent a car at Fresno Yosemite International Airport book yours with your flight.
Yes! Flights from Knoxville to Fresno—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.
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