Southwest® flights from Knoxville to Destin/Fort Walton Beach from $109

Promo Code

Low fares from Knoxville to Destin/Fort Walton Beach

$

Knoxville (TYS)to

Destin/Fort Walton Beach (VPS)
Depart: 10/24/2026

One-way

Basic

From
$109

Low fares from Knoxville to Destin/Fort Walton Beach

$

Knoxville (TYS)to

Destin/Fort Walton Beach (VPS)
Depart: 10/24/2026

One-way

Basic

From
$109
Seen: 10 hrs ago

Knoxville (TYS)to

Destin/Fort Walton Beach (VPS)
Depart: 10/24/2026

One-way

Choice

From
$146
Seen: 10 hrs ago

Knoxville (TYS)to

Destin/Fort Walton Beach (VPS)
Depart: 11/26/2026

One-way

Basic

From
$165
Seen: 11 hrs ago

Knoxville (TYS)to

Destin/Fort Walton Beach (VPS)
Depart: 10/25/2026

One-way

Basic

From
$184
Seen: 3 hrs ago

Knoxville (TYS)to

Destin/Fort Walton Beach (VPS)
Depart: 11/26/2026

One-way

Choice

From
$200
Seen: 11 hrs ago

Knoxville (TYS)to

Destin/Fort Walton Beach (VPS)
Depart: 11/22/2026

One-way

Basic

From
$204
Seen: 5 hrs ago

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Explore flights from Knoxville to Destin/Fort Walton Beach

Sep 2026
From$220*
Seen: 3 hrs ago
One Way/Basic
Oct 2026
From$109*
Seen: 10 hrs ago
One Way/Basic
Nov 2026
From$165*
Seen: 11 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $220
cmp-daily-histogram-bars-legend-max-price-aria-label $504
Displaying fares for September-2026
  • TYS–VPS, 09/18/2026: From $297
    18

    Fri

    SEP

  • TYS–VPS, 09/19/2026: From $220
    19

    Sat

  • TYS–VPS, 09/20/2026: From $504
    20

    Sun

  • TYS–VPS, 09/21/2026: From $297
    21

    Mon

  • TYS–VPS, 09/22/2026: From $220
    22

    Tue

  • TYS–VPS, 09/23/2026: From $220
    23

    Wed

  • TYS–VPS: cmp-view-offers-disclaimer. Find Offers
    24

    Thu

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    25

    Fri

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    26

    Sat

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    27

    Sun

  • TYS–VPS: cmp-view-offers-disclaimer. Find Offers
    28

    Mon

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    29

    Tue

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    30

    Wed

  • TYS–VPS, 10/01/2026: From $245
    01

    Thu

    OCT

  • TYS–VPS: cmp-view-offers-disclaimer. Find Offers
    02

    Fri

  • TYS–VPS, 10/03/2026: From $302
    03

    Sat

  • TYS–VPS: cmp-view-offers-disclaimer. Find Offers
    04

    Sun

  • TYS–VPS, 10/05/2026: From $239
    05

    Mon

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    06

    Tue

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    07

    Wed

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    08

    Thu

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    09

    Fri

  • TYS–VPS, 10/10/2026: From $249
    10

    Sat

  • TYS–VPS: cmp-view-offers-disclaimer. Find Offers
    11

    Sun

  • TYS–VPS: cmp-view-offers-disclaimer. Find Offers
    12

    Mon

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    13

    Tue

  • TYS–VPS: cmp-view-offers-disclaimer. Find Offers
    14

    Wed

  • TYS–VPS: cmp-view-offers-disclaimer. Find Offers
    15

    Thu

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    16

    Fri

  • TYS–VPS: cmp-view-offers-disclaimer. Find Offers
    17

    Sat

    • Range$220-$504

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Mc Ghee Tyson Airport
    Arriving at:
    Destin–Fort Walton Beach Airport
    Distance:
    395 miles

    Route Information

    42† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 42 weekly flights from Knoxville to Destin/Fort Walton Beach on Southwest Airlines.
    To find the lowest fares by day and time to fly Knoxville to Destin/Fort Walton Beach with Southwest, check out our Low Fare Calendar.
    You can rent a car at Destin–Fort Walton Beach Airport book yours with your flight.
    Yes! Flights from Knoxville to Destin/Fort Walton Beach—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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