Southwest® flights from Knoxville to New York (LaGuardia) from $144

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Low fares from Knoxville to New York (LaGuardia)

$

Knoxville (TYS)to

New York (LaGuardia) (LGA)
Depart: 12/15/2026

One-way

Basic

From
$144

Low fares from Knoxville to New York (LaGuardia)

$

Knoxville (TYS)to

New York (LaGuardia) (LGA)
Depart: 10/28/2026

One-way

Basic

From
$144
Seen: 2 hrs ago

Knoxville (TYS)to

New York (LaGuardia) (LGA)
Depart: 11/18/2026

One-way

Basic

From
$160
Seen: 48 minutes ago

Knoxville (TYS)to

New York (LaGuardia) (LGA)
Depart: 10/31/2026

One-way

Basic

From
$165
Seen: 40 minutes ago

Knoxville (TYS)to

New York (LaGuardia) (LGA)
Depart: 10/28/2026

One-way

Choice

From
$184
Seen: 2 hrs ago

Knoxville (TYS)to

New York (LaGuardia) (LGA)
Depart: 11/19/2026

One-way

Basic

From
$195
Seen: 49 minutes ago

Knoxville (TYS)to

New York (LaGuardia) (LGA)
Depart: 11/18/2026

One-way

Choice

From
$200
Seen: 48 minutes ago

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Explore flights from Knoxville to New York (LaGuardia)

Aug 2026
From$394*
Seen: 16 hrs ago
One Way/Basic
Sep 2026
From$205*
Seen: 22 hrs ago
One Way/Basic
Oct 2026
From$144*
Seen: 2 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $205
Displaying fares for August-2026
  • TYS–LGA, 08/28/2026: From $394
    28

    Fri

    AUG

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    29

    Sat

  • TYS–LGA, 08/30/2026: From $394
    30

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    31

    Mon

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    03

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    04

    Fri

  • TYS–LGA, 09/05/2026: From $305
    05

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    06

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    07

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    08

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    09

    Wed

  • TYS–LGA, 09/10/2026: From $205
    10

    Thu

  • TYS–LGA, 09/11/2026: From $205
    11

    Fri

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    12

    Sat

  • TYS–LGA, 09/13/2026: From $318
    13

    Sun

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    14

    Mon

  • TYS–LGA, 09/15/2026: From $234
    15

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    16

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    17

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    18

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    19

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    20

    Sun

  • TYS–LGA, 09/21/2026: From $349
    21

    Mon

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    22

    Tue

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    23

    Wed

  • TYS–LGA, 09/24/2026: From $244
    24

    Thu

  • TYS–LGA: cmp-view-offers-disclaimer. Find Offers
    25

    Fri

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    26

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    27

    Sun

    • Range$205-$394

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Mc Ghee Tyson Airport
    Arriving at:
    La Guardia Airport
    Distance:
    647 miles

    Route Information

    45† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 45 weekly flights from Knoxville to New York (LaGuardia) on Southwest Airlines.
    To find the lowest fares by day and time to fly Knoxville to New York (LaGuardia) with Southwest, check out our Low Fare Calendar.
    You can rent a car at La Guardia Airport book yours with your flight.
    Yes! Flights from Knoxville to New York (LaGuardia)—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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