Southwest® flights from Knoxville to Tampa from $109

Promo Code

Low fares from Knoxville to Tampa

$

Knoxville (TYS)to

Tampa (TPA)
Depart: 11/23/2026

One-way

Basic

From
$109

Low fares from Knoxville to Tampa

$

Knoxville (TYS)to

Tampa (TPA)
Depart: 11/23/2026

One-way

Basic

From
$109
Seen: 15 minutes ago

Knoxville (TYS)to

Tampa (TPA)
Depart: 12/12/2026

One-way

Basic

From
$116
Seen: 16 hrs ago

Knoxville (TYS)to

Tampa (TPA)
Depart: 10/31/2026

One-way

Basic

From
$116
Seen: 17 hrs ago

Knoxville (TYS)to

Tampa (TPA)
Depart: 11/23/2026

One-way

Choice

From
$149
Seen: 15 minutes ago

Knoxville (TYS)to

Tampa (TPA)
Depart: 12/12/2026

One-way

Choice

From
$157
Seen: 16 hrs ago

Knoxville (TYS)to

Tampa (TPA)
Depart: 10/31/2026

One-way

Choice

From
$157
Seen: 17 hrs ago

Looking for more low-fare flights?

Check out the Low Fare Calendar to find a fare that works for you. Just choose the month you want to depart and return, and we’ll show you the best fares available.

Find low fares

Explore flights from Knoxville to Tampa

Oct 2026
From$116*
Seen: 17 hrs ago
One Way/Basic
Nov 2026
From$109*
Seen: 15 minutes ago
One Way/Basic
Dec 2026
From$116*
Seen: 16 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $116
cmp-daily-histogram-bars-legend-max-price-aria-label $344
Displaying fares for October-2026
  • TYS–TPA: cmp-view-offers-disclaimer. Find Offers
    09

    Fri

    OCT

  • TYS–TPA, 10/10/2026: From $339
    10

    Sat

  • TYS–TPA, 10/11/2026: From $344
    11

    Sun

  • TYS–TPA, 10/12/2026: From $339
    12

    Mon

  • TYS–TPA: cmp-view-offers-disclaimer. Find Offers
    13

    Tue

  • TYS–TPA, 10/14/2026: From $334
    14

    Wed

  • TYS–TPA, 10/15/2026: From $334
    15

    Thu

  • TYS–TPA: cmp-view-offers-disclaimer. Find Offers
    16

    Fri

  • TYS–TPA: cmp-view-offers-disclaimer. Find Offers
    17

    Sat

  • TYS–TPA: cmp-view-offers-disclaimer. Find Offers
    18

    Sun

  • TYS–TPA, 10/19/2026: From $334
    19

    Mon

  • TYS–TPA: cmp-view-offers-disclaimer. Find Offers
    20

    Tue

  • TYS–TPA, 10/21/2026: From $334
    21

    Wed

  • TYS–TPA: cmp-view-offers-disclaimer. Find Offers
    22

    Thu

  • TYS–TPA, 10/23/2026: From $240
    23

    Fri

  • TYS–TPA, 10/24/2026: From $250
    24

    Sat

  • TYS–TPA: cmp-view-offers-disclaimer. Find Offers
    25

    Sun

  • TYS–TPA, 10/26/2026: From $240
    26

    Mon

  • TYS–TPA, 10/27/2026: From $159
    27

    Tue

  • TYS–TPA: cmp-view-offers-disclaimer. Find Offers
    28

    Wed

  • TYS–TPA: cmp-view-offers-disclaimer. Find Offers
    29

    Thu

  • TYS–TPA, 10/30/2026: From $171
    30

    Fri

  • TYS–TPA, 10/31/2026: From $116
    31

    Sat

  • TYS–TPA, 11/01/2026: From $216
    01

    Sun

    NOV

  • TYS–TPA, 11/02/2026: From $208
    02

    Mon

  • TYS–TPA: cmp-view-offers-disclaimer. Find Offers
    03

    Tue

  • TYS–TPA: cmp-view-offers-disclaimer. Find Offers
    04

    Wed

  • TYS–TPA, 11/05/2026: From $208
    05

    Thu

  • TYS–TPA: cmp-view-offers-disclaimer. Find Offers
    06

    Fri

  • TYS–TPA: cmp-view-offers-disclaimer. Find Offers
    07

    Sat

  • TYS–TPA: cmp-view-offers-disclaimer. Find Offers
    08

    Sun

    • Range$116-$344

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Mc Ghee Tyson Airport
    Arriving at:
    Tampa International Airport
    Distance:
    547 miles

    Questions we hear the most

    There are 52 weekly flights from Knoxville to Tampa on Southwest Airlines.
    To find the lowest fares by day and time to fly Knoxville to Tampa with Southwest, check out our Low Fare Calendar.
    You can rent a car at Tampa International Airport book yours with your flight.
    Yes! Flights from Knoxville to Tampa—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

    Explore Flights from Other Popular Origins

    Popular Flights from Knoxville