Southwest® flights from Des Moines to Charlotte from $194

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Low fares from Des Moines to Charlotte

$

Des Moines (DSM)to

Charlotte (CLT)
Depart: 01/16/2027

One-way

Basic

From
$194
Seen: 10 hrs ago

Des Moines (DSM)to

Charlotte (CLT)
Depart: 02/13/2027

One-way

Basic

From
$194
Seen: 10 hrs ago

Des Moines (DSM)to

Charlotte (CLT)
Depart: 12/16/2026

One-way

Basic

From
$194
Seen: 2 hrs ago

Des Moines (DSM)to

Charlotte (CLT)
Depart: 01/04/2027

One-way

Basic

From
$214
Seen: 9 hrs ago

Des Moines (DSM)to

Charlotte (CLT)
Depart: 12/03/2026

One-way

Basic

From
$214
Seen: 5 hrs ago

Des Moines (DSM)to

Charlotte (CLT)
Depart: 12/22/2026

One-way

Basic

From
$219
Seen: 2 hrs ago

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Explore flights from Des Moines to Charlotte

Nov 2026
From$273*
Seen: 18 hrs ago
One Way/Basic
Dec 2026
From$194*
Seen: 2 hrs ago
One Way/Basic
Jan 2027
From$194*
Seen: 10 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $214
cmp-daily-histogram-bars-legend-max-price-aria-label $313
Displaying fares for November-2026
  • DSM–CLT: cmp-view-offers-disclaimer. Find Offers
    13

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    NOV

  • DSM–CLT: cmp-view-offers-disclaimer. Find Offers
    14

    Sat

  • DSM–CLT, 11/15/2026: From $313
    15

    Sun

  • DSM–CLT, 11/16/2026: From $308
    16

    Mon

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    17

    Tue

  • DSM–CLT, 11/18/2026: From $273
    18

    Wed

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    19

    Thu

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    20

    Fri

  • DSM–CLT, 11/21/2026: From $278
    21

    Sat

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    22

    Sun

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    23

    Mon

  • DSM–CLT: cmp-view-offers-disclaimer. Find Offers
    24

    Tue

  • DSM–CLT, 11/25/2026: From $278
    25

    Wed

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    26

    Thu

  • DSM–CLT: cmp-view-offers-disclaimer. Find Offers
    27

    Fri

  • DSM–CLT: cmp-view-offers-disclaimer. Find Offers
    28

    Sat

  • DSM–CLT: cmp-view-offers-disclaimer. Find Offers
    29

    Sun

  • DSM–CLT, 11/30/2026: From $308
    30

    Mon

  • DSM–CLT, 12/01/2026: From $273
    01

    Tue

    DEC

  • DSM–CLT, 12/02/2026: From $278
    02

    Wed

  • DSM–CLT, 12/03/2026: From $214
    03

    Thu

  • DSM–CLT, 12/04/2026: From $234
    04

    Fri

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    05

    Sat

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    06

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    07

    Mon

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    08

    Tue

  • DSM–CLT: cmp-view-offers-disclaimer. Find Offers
    09

    Wed

  • DSM–CLT: cmp-view-offers-disclaimer. Find Offers
    10

    Thu

  • DSM–CLT: cmp-view-offers-disclaimer. Find Offers
    11

    Fri

  • DSM–CLT: cmp-view-offers-disclaimer. Find Offers
    12

    Sat

    • Range$214-$313

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Des Moines Airport
    Arriving at:
    Douglas Airport
    Distance:
    815 miles

    Questions we hear the most

    There are 32 weekly flights from Des Moines to Charlotte on Southwest Airlines.
    To find the lowest fares by day and time to fly Des Moines to Charlotte with Southwest, check out our Low Fare Calendar.
    You can rent a car at Douglas Airport book yours with your flight.
    Yes! Flights from Des Moines to Charlotte—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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