Southwest® flights from Des Moines to Orange County/Santa Ana from $194

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Low fares from Des Moines to Orange County/Santa Ana

$

Des Moines (DSM)to

Orange County/Santa Ana (SNA)
Depart: 12/09/2026

One-way

Basic

From
$194
Seen: 2 hrs ago

Des Moines (DSM)to

Orange County/Santa Ana (SNA)
Depart: 12/07/2026

One-way

Basic

From
$214
Seen: 2 hrs ago

Des Moines (DSM)to

Orange County/Santa Ana (SNA)
Depart: 01/12/2027

One-way

Basic

From
$214
Seen: 4 hrs ago

Des Moines (DSM)to

Orange County/Santa Ana (SNA)
Depart: 12/08/2026

One-way

Basic

From
$234
Seen: 3 hrs ago

Des Moines (DSM)to

Orange County/Santa Ana (SNA)
Depart: 12/10/2026

One-way

Basic

From
$234
Seen: 2 hrs ago

Des Moines (DSM)to

Orange County/Santa Ana (SNA)
Depart: 12/24/2026

One-way

Basic

From
$234
Seen: 11 hrs ago

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Explore flights from Des Moines to Orange County/Santa Ana

Nov 2026
From$314*
Seen: 23 hrs ago
One Way/Basic
Dec 2026
From$194*
Seen: 2 hrs ago
One Way/Basic
Jan 2027
From$214*
Seen: 4 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $194
cmp-daily-histogram-bars-legend-max-price-aria-label $579
Displaying fares for November-2026
  • DSM–SNA, 11/13/2026: From $579
    13

    Fri

    NOV

  • DSM–SNA, 11/14/2026: From $579
    14

    Sat

  • DSM–SNA: cmp-view-offers-disclaimer. Find Offers
    15

    Sun

  • DSM–SNA: cmp-view-offers-disclaimer. Find Offers
    16

    Mon

  • DSM–SNA: cmp-view-offers-disclaimer. Find Offers
    17

    Tue

  • DSM–SNA: cmp-view-offers-disclaimer. Find Offers
    18

    Wed

  • DSM–SNA: cmp-view-offers-disclaimer. Find Offers
    19

    Thu

  • DSM–SNA: cmp-view-offers-disclaimer. Find Offers
    20

    Fri

  • DSM–SNA: cmp-view-offers-disclaimer. Find Offers
    21

    Sat

  • DSM–SNA, 11/22/2026: From $489
    22

    Sun

  • DSM–SNA: cmp-view-offers-disclaimer. Find Offers
    23

    Mon

  • DSM–SNA: cmp-view-offers-disclaimer. Find Offers
    24

    Tue

  • DSM–SNA, 11/25/2026: From $489
    25

    Wed

  • DSM–SNA: cmp-view-offers-disclaimer. Find Offers
    26

    Thu

  • DSM–SNA, 11/27/2026: From $314
    27

    Fri

  • DSM–SNA: cmp-view-offers-disclaimer. Find Offers
    28

    Sat

  • DSM–SNA: cmp-view-offers-disclaimer. Find Offers
    29

    Sun

  • DSM–SNA: cmp-view-offers-disclaimer. Find Offers
    30

    Mon

  • DSM–SNA: cmp-view-offers-disclaimer. Find Offers
    01

    Tue

    DEC

  • DSM–SNA, 12/02/2026: From $319
    02

    Wed

  • DSM–SNA: cmp-view-offers-disclaimer. Find Offers
    03

    Thu

  • DSM–SNA: cmp-view-offers-disclaimer. Find Offers
    04

    Fri

  • DSM–SNA: cmp-view-offers-disclaimer. Find Offers
    05

    Sat

  • DSM–SNA: cmp-view-offers-disclaimer. Find Offers
    06

    Sun

  • DSM–SNA, 12/07/2026: From $214
    07

    Mon

  • DSM–SNA, 12/08/2026: From $234
    08

    Tue

  • DSM–SNA, 12/09/2026: From $194
    09

    Wed

  • DSM–SNA, 12/10/2026: From $234
    10

    Thu

  • DSM–SNA: cmp-view-offers-disclaimer. Find Offers
    11

    Fri

  • DSM–SNA: cmp-view-offers-disclaimer. Find Offers
    12

    Sat

    • Range$194-$579

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Des Moines Airport
    Arriving at:
    John Wayne Airport
    Distance:
    1429 miles

    Questions we hear the most

    There are 65 weekly flights from Des Moines to Orange County/Santa Ana on Southwest Airlines.
    To find the lowest fares by day and time to fly Des Moines to Orange County/Santa Ana with Southwest, check out our Low Fare Calendar.
    You can rent a car at John Wayne Airport book yours with your flight.
    Yes! Flights from Des Moines to Orange County/Santa Ana—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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