Southwest® flights from Des Moines to Las Vegas from $152

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Low fares from Des Moines to Las Vegas

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Des Moines (DSM)to

Las Vegas (LAS)
Depart: 03/07/2026

One-way

Basic

From
$152
Seen: 1 hour ago

Des Moines (DSM)to

Las Vegas (LAS)
Depart: 03/28/2026

One-way

Basic

From
$152
Seen: 2 hrs ago

Des Moines (DSM)to

Las Vegas (LAS)
Depart: 04/01/2026

One-way

Basic

From
$153
Seen: 21 hrs ago

Des Moines (DSM)to

Las Vegas (LAS)
Depart: 04/21/2026

One-way

Basic

From
$154
Seen: 11 hrs ago

Des Moines (DSM)to

Las Vegas (LAS)
Depart: 05/06/2026

One-way

Basic

From
$154
Seen: 6 hrs ago

Des Moines (DSM)to

Las Vegas (LAS)
Depart: 04/27/2026

One-way

Basic

From
$154
Seen: 22 hrs ago
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Flight Details

Departing from:
Des Moines Airport
Arriving at:
McCarran International Airport
Average flight time:
3 hours 12 minutes
Distance:
1216 miles

Route Information

83 Weekly flights
  • 1 Nonstop flight per day Monday through Friday
  • 1 Nonstop flight on Saturday
  • 1 Nonstop flight on Sunday

† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

Questions we hear the most

The average flight time from Des Moines to Las Vegas is 3 hours 12 minutes.
There are 83 weekly flights from Des Moines to Las Vegas on Southwest Airlines.
Yes, Southwest flies nonstop from Des Moines to Las Vegas once per day from Monday through Friday.
Yes, Southwest flies nonstop from Des Moines to Las Vegas once per day on Saturdays and Sundays.
To find the lowest fares by day and time to fly Des Moines to Las Vegas with Southwest, check out our Low Fare Calendar.
You can rent a car at McCarran International Airport book yours with your flight.
Yes! Flights from Des Moines to Las Vegas—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.

Popular Flights from Des Moines