Southwest® flights from Des Moines to Palm Springs from $295

Promo Code

Low fares from Des Moines to Palm Springs

$

Des Moines (DSM)to

Palm Springs (PSP)
Depart: 09/30/2026

One-way

Basic

From
$174
Seen: 12 hrs ago

Des Moines (DSM)to

Palm Springs (PSP)
Depart: 09/30/2026

One-way

Choice

From
$219
Seen: 12 hrs ago

Des Moines (DSM)to

Palm Springs (PSP)
Depart: 07/11/2026

One-way

Basic

From
$295
Seen: 11 hrs ago

Des Moines (DSM)to

Palm Springs (PSP)
Depart: 09/30/2026

One-way

Choice Preferred

From
$299
Seen: 12 hrs ago

Des Moines (DSM)to

Palm Springs (PSP)
Depart: 07/13/2026

One-way

Basic

From
$300
Seen: 19 hrs ago

Des Moines (DSM)to

Palm Springs (PSP)
Depart: 06/30/2026

One-way

Basic

From
$302
Seen: 16 hrs ago

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Explore flights from Des Moines to Palm Springs

Jun 2026
From$302*
Seen: 16 hrs ago
One Way/Basic
Jul 2026
From$295*
Seen: 11 hrs ago
One Way/Basic
Aug 2026
No result for this month.
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    • Range$295-$457

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Des Moines Airport
    Arriving at:
    Palm Springs International Airport
    Distance:
    1355 miles

    Route Information

    36† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 36 weekly flights from Des Moines to Palm Springs on Southwest Airlines.
    To find the lowest fares by day and time to fly Des Moines to Palm Springs with Southwest, check out our Low Fare Calendar.
    You can rent a car at Palm Springs International Airport book yours with your flight.
    Yes! Flights from Des Moines to Palm Springs—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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