Southwest® flights from Des Moines to Columbus from $155

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Low fares from Des Moines to Columbus

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Des Moines (DSM)to

Columbus (CMH)
Depart: 08/25/2026

One-way

Basic

From
$155
Seen: 3 hrs ago

Des Moines (DSM)to

Columbus (CMH)
Depart: 08/26/2026

One-way

Basic

From
$155
Seen: 4 hrs ago

Des Moines (DSM)to

Columbus (CMH)
Depart: 09/22/2026

One-way

Basic

From
$168
Seen: 10 hrs ago

Des Moines (DSM)to

Columbus (CMH)
Depart: 10/02/2026

One-way

Basic

From
$184
Seen: 22 hrs ago

Des Moines (DSM)to

Columbus (CMH)
Depart: 08/21/2026

One-way

Basic

From
$184
Seen: 8 hrs ago

Des Moines (DSM)to

Columbus (CMH)
Depart: 09/18/2026

One-way

Basic

From
$189
Seen: 6 hrs ago

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Explore flights from Des Moines to Columbus

Aug 2026
From$155*
Seen: 3 hrs ago
One Way/Basic
Sep 2026
From$168*
Seen: 10 hrs ago
One Way/Basic
Oct 2026
From$184*
Seen: 22 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $155
cmp-daily-histogram-bars-legend-max-price-aria-label $602
Displaying fares for August-2026
  • DSM–CMH, 08/01/2026: From $268
    01

    Sat

    AUG

  • DSM–CMH, 08/02/2026: From $349
    02

    Sun

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    03

    Mon

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    04

    Tue

  • DSM–CMH, 08/05/2026: From $309
    05

    Wed

  • DSM–CMH, 08/06/2026: From $339
    06

    Thu

  • DSM–CMH, 08/07/2026: From $334
    07

    Fri

  • DSM–CMH, 08/08/2026: From $602
    08

    Sat

  • DSM–CMH: cmp-view-offers-disclaimer. Find Offers
    09

    Sun

  • DSM–CMH, 08/10/2026: From $334
    10

    Mon

  • DSM–CMH: cmp-view-offers-disclaimer. Find Offers
    11

    Tue

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    12

    Wed

  • DSM–CMH, 08/13/2026: From $334
    13

    Thu

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    14

    Fri

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    15

    Sat

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    16

    Sun

  • DSM–CMH, 08/17/2026: From $239
    17

    Mon

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    18

    Tue

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    19

    Wed

  • DSM–CMH, 08/20/2026: From $200
    20

    Thu

  • DSM–CMH, 08/21/2026: From $184
    21

    Fri

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    22

    Sat

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    23

    Sun

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    24

    Mon

  • DSM–CMH, 08/25/2026: From $155
    25

    Tue

  • DSM–CMH, 08/26/2026: From $155
    26

    Wed

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    27

    Thu

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    28

    Fri

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    29

    Sat

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    30

    Sun

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    31

    Mon

    • Range$155-$602

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Des Moines Airport
    Arriving at:
    Port Columbus International Airport
    Distance:
    574 miles

    Route Information

    48† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 48 weekly flights from Des Moines to Columbus on Southwest Airlines.
    To find the lowest fares by day and time to fly Des Moines to Columbus with Southwest, check out our Low Fare Calendar.
    You can rent a car at Port Columbus International Airport book yours with your flight.
    Yes! Flights from Des Moines to Columbus—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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