Southwest® flights from Des Moines to New Orleans from $134

Promo Code

Low fares from Des Moines to New Orleans

$

Des Moines (DSM)to

New Orleans (MSY)
Depart: 12/16/2026

One-way

Basic

From
$134
Seen: 2 hrs ago

Des Moines (DSM)to

New Orleans (MSY)
Depart: 12/23/2026

One-way

Basic

From
$134
Seen: 2 hrs ago

Des Moines (DSM)to

New Orleans (MSY)
Depart: 11/14/2026

One-way

Basic

From
$139
Seen: 4 hrs ago

Des Moines (DSM)to

New Orleans (MSY)
Depart: 12/16/2026

One-way

Choice

From
$177
Seen: 2 hrs ago

Des Moines (DSM)to

New Orleans (MSY)
Depart: 12/23/2026

One-way

Choice

From
$177
Seen: 2 hrs ago

Des Moines (DSM)to

New Orleans (MSY)
Depart: 11/14/2026

One-way

Choice

From
$183
Seen: 4 hrs ago

Looking for more low-fare flights?

Check out the Low Fare Calendar to find a fare that works for you. Just choose the month you want to depart and return, and we’ll show you the best fares available.

Find low fares

Explore flights from Des Moines to New Orleans

Oct 2026
From$315*
Seen: 1 hour ago
One Way/Basic
Nov 2026
From$139*
Seen: 4 hrs ago
One Way/Basic
Dec 2026
From$134*
Seen: 2 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $139
Displaying fares for October-2026
  • DSM–MSY, 10/21/2026: From $315
    21

    Wed

    OCT

  • DSM–MSY, 10/22/2026: From $361
    22

    Thu

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    23

    Fri

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    24

    Sat

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    25

    Sun

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    26

    Mon

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    27

    Tue

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    28

    Wed

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    29

    Thu

  • DSM–MSY, 10/30/2026: From $361
    30

    Fri

  • DSM–MSY, 10/31/2026: From $315
    31

    Sat

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    01

    Sun

    NOV

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    02

    Mon

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    03

    Tue

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    04

    Wed

  • DSM–MSY, 11/05/2026: From $445
    05

    Thu

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    06

    Fri

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    07

    Sat

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    08

    Sun

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    09

    Mon

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    10

    Tue

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    11

    Wed

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    12

    Thu

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    13

    Fri

  • DSM–MSY, 11/14/2026: From $139
    14

    Sat

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    15

    Sun

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    16

    Mon

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    17

    Tue

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    18

    Wed

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    19

    Thu

  • DSM–MSY: cmp-view-offers-disclaimer. Find Offers
    20

    Fri

    • Range$139-$445

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Des Moines Airport
    Arriving at:
    Louis Armstrong International Airport
    Distance:
    818 miles

    Questions we hear the most

    There are 68 weekly flights from Des Moines to New Orleans on Southwest Airlines.
    To find the lowest fares by day and time to fly Des Moines to New Orleans with Southwest, check out our Low Fare Calendar.
    You can rent a car at Louis Armstrong International Airport book yours with your flight.
    Yes! Flights from Des Moines to New Orleans—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

    Explore Flights from Other Popular Origins

    Popular Flights from Des Moines