Southwest® flights from Des Moines to Phoenix from $157

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Low fares from Des Moines to Phoenix

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Des Moines (DSM)to

Phoenix (PHX)
Depart: 12/15/2026

One-way

Basic

From
$157
Seen: 23 hrs ago

Des Moines (DSM)to

Phoenix (PHX)
Depart: 01/05/2027

One-way

Basic

From
$157
Seen: 12 hrs ago

Des Moines (DSM)to

Phoenix (PHX)
Depart: 01/06/2027

One-way

Basic

From
$157
Seen: 5 hrs ago

Des Moines (DSM)to

Phoenix (PHX)
Depart: 02/03/2027

One-way

Basic

From
$157
Seen: 1 hour ago

Des Moines (DSM)to

Phoenix (PHX)
Depart: 12/09/2026

One-way

Basic

From
$157
Seen: 2 hrs ago

Des Moines (DSM)to

Phoenix (PHX)
Depart: 02/12/2027

One-way

Basic

From
$187
Seen: 17 hrs ago
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Explore flights from Des Moines to Phoenix

cmp-daily-histogram-bars-legend-min-price-aria-label $157
cmp-daily-histogram-bars-legend-max-price-aria-label $301
Displaying fares for November-2026
  • DSM–PHX, 11/10/2026: From $276
    10

    Tue

    NOV

  • DSM–PHX: cmp-view-offers-disclaimer. Find Offers
    11

    Wed

  • DSM–PHX: cmp-view-offers-disclaimer. Find Offers
    12

    Thu

  • DSM–PHX: cmp-view-offers-disclaimer. Find Offers
    13

    Fri

  • DSM–PHX: cmp-view-offers-disclaimer. Find Offers
    14

    Sat

  • DSM–PHX, 11/15/2026: From $291
    15

    Sun

  • DSM–PHX, 11/16/2026: From $301
    16

    Mon

  • DSM–PHX, 11/17/2026: From $276
    17

    Tue

  • DSM–PHX: cmp-view-offers-disclaimer. Find Offers
    18

    Wed

  • DSM–PHX, 11/19/2026: From $301
    19

    Thu

  • DSM–PHX, 11/20/2026: From $291
    20

    Fri

  • DSM–PHX: cmp-view-offers-disclaimer. Find Offers
    21

    Sat

  • DSM–PHX, 11/22/2026: From $291
    22

    Sun

  • DSM–PHX, 11/23/2026: From $291
    23

    Mon

  • DSM–PHX: cmp-view-offers-disclaimer. Find Offers
    24

    Tue

  • DSM–PHX, 11/25/2026: From $266
    25

    Wed

  • DSM–PHX: cmp-view-offers-disclaimer. Find Offers
    26

    Thu

  • DSM–PHX, 11/27/2026: From $291
    27

    Fri

  • DSM–PHX: cmp-view-offers-disclaimer. Find Offers
    28

    Sat

  • DSM–PHX, 11/29/2026: From $291
    29

    Sun

  • DSM–PHX, 11/30/2026: From $291
    30

    Mon

  • DSM–PHX, 12/01/2026: From $201
    01

    Tue

    DEC

  • DSM–PHX, 12/02/2026: From $201
    02

    Wed

  • DSM–PHX: cmp-view-offers-disclaimer. Find Offers
    03

    Thu

  • DSM–PHX, 12/04/2026: From $226
    04

    Fri

  • DSM–PHX: cmp-view-offers-disclaimer. Find Offers
    05

    Sat

  • DSM–PHX, 12/06/2026: From $265
    06

    Sun

  • DSM–PHX: cmp-view-offers-disclaimer. Find Offers
    07

    Mon

  • DSM–PHX: cmp-view-offers-disclaimer. Find Offers
    08

    Tue

  • DSM–PHX, 12/09/2026: From $157
    09

    Wed

  • Range$157-$301

    Flight Details

    Departing from:
    Des Moines Airport
    Arriving at:
    Sky Harbor International Airport
    Average flight time:
    3 hours 4 minutes
    Distance:
    1150 miles

    Questions we hear the most

    The average flight time from Des Moines to Phoenix is 3 hours 4 minutes.
    There are 82 weekly flights from Des Moines to Phoenix on Southwest Airlines.
    Yes, Southwest flies nonstop from Des Moines to Phoenix once per day from Monday through Friday.
    Yes, Southwest flies nonstop from Des Moines to Phoenix once per day on Saturdays and Sundays.
    To find the lowest fares by day and time to fly Des Moines to Phoenix with Southwest, check out our Low Fare Calendar.
    You can rent a car at Sky Harbor International Airport book yours with your flight.
    Yes! Flights from Des Moines to Phoenix—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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