Southwest® flights from Des Moines to Denver from $142

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Low fares from Des Moines to Denver

$

Des Moines (DSM)to

Denver (DEN)
Depart: 11/24/2026

One-way

Basic

From
$142
Seen: 22 hrs ago

Des Moines (DSM)to

Denver (DEN)
Depart: 11/12/2026

One-way

Basic

From
$142
Seen: 15 hrs ago

Des Moines (DSM)to

Denver (DEN)
Depart: 10/19/2026

One-way

Basic

From
$142
Seen: 13 hrs ago

Des Moines (DSM)to

Denver (DEN)
Depart: 12/01/2026

One-way

Basic

From
$142
Seen: 4 hrs ago

Des Moines (DSM)to

Denver (DEN)
Depart: 12/08/2026

One-way

Basic

From
$142
Seen: 19 hrs ago

Des Moines (DSM)to

Denver (DEN)
Depart: 10/21/2026

One-way

Basic

From
$142
Seen: 17 hrs ago

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Explore flights from Des Moines to Denver

Sep 2026
From$492*
Seen: 19 hrs ago
One Way/Basic
Oct 2026
From$142*
Seen: 17 hrs ago
One Way/Basic
Nov 2026
From$142*
Seen: 18 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $142
cmp-daily-histogram-bars-legend-max-price-aria-label $492
Displaying fares for September-2026
  • DSM–DEN, 09/30/2026: From $492
    30

    Wed

    SEP

  • DSM–DEN: cmp-view-offers-disclaimer. Find Offers
    01

    Thu

  • DSM–DEN, 10/02/2026: From $492
    02

    Fri

  • DSM–DEN, 10/03/2026: From $492
    03

    Sat

  • DSM–DEN, 10/04/2026: From $492
    04

    Sun

  • DSM–DEN, 10/05/2026: From $492
    05

    Mon

  • DSM–DEN, 10/06/2026: From $390
    06

    Tue

  • DSM–DEN, 10/07/2026: From $390
    07

    Wed

  • DSM–DEN, 10/08/2026: From $390
    08

    Thu

  • DSM–DEN, 10/09/2026: From $390
    09

    Fri

  • DSM–DEN: cmp-view-offers-disclaimer. Find Offers
    10

    Sat

  • DSM–DEN: cmp-view-offers-disclaimer. Find Offers
    11

    Sun

  • DSM–DEN, 10/12/2026: From $225
    12

    Mon

  • DSM–DEN, 10/13/2026: From $225
    13

    Tue

  • DSM–DEN: cmp-view-offers-disclaimer. Find Offers
    14

    Wed

  • DSM–DEN, 10/15/2026: From $225
    15

    Thu

  • DSM–DEN, 10/16/2026: From $225
    16

    Fri

  • DSM–DEN: cmp-view-offers-disclaimer. Find Offers
    17

    Sat

  • DSM–DEN, 10/18/2026: From $225
    18

    Sun

  • DSM–DEN, 10/19/2026: From $142
    19

    Mon

  • DSM–DEN, 10/20/2026: From $142
    20

    Tue

  • DSM–DEN, 10/21/2026: From $142
    21

    Wed

  • DSM–DEN, 10/22/2026: From $160
    22

    Thu

  • DSM–DEN, 10/23/2026: From $160
    23

    Fri

  • DSM–DEN: cmp-view-offers-disclaimer. Find Offers
    24

    Sat

  • DSM–DEN: cmp-view-offers-disclaimer. Find Offers
    25

    Sun

  • DSM–DEN: cmp-view-offers-disclaimer. Find Offers
    26

    Mon

  • DSM–DEN: cmp-view-offers-disclaimer. Find Offers
    27

    Tue

  • DSM–DEN, 10/28/2026: From $142
    28

    Wed

  • DSM–DEN, 10/29/2026: From $142
    29

    Thu

    • Range$142-$492

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Des Moines Airport
    Arriving at:
    Denver International Airport
    Average flight time:
    1 hour 58 minutes
    Distance:
    589 miles

    Route Information

    69† Weekly flights
    • 1‡ Nonstop flight per day Monday through Friday
    • 1‡ Nonstop flight on Saturday
    • 1‡ Nonstop flight on Sunday

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    The average flight time from Des Moines to Denver is 1 hour 58 minutes.
    There are 69 weekly flights from Des Moines to Denver on Southwest Airlines.
    Yes, Southwest flies nonstop from Des Moines to Denver once per day from Monday through Friday.
    Yes, Southwest flies nonstop from Des Moines to Denver once per day on Saturdays and Sundays.
    To find the lowest fares by day and time to fly Des Moines to Denver with Southwest, check out our Low Fare Calendar.
    You can rent a car at Denver International Airport book yours with your flight.
    Yes! Flights from Des Moines to Denver—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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