Southwest® flights from Des Moines to Denver from $135

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Low fares from Des Moines to Denver

$

Des Moines (DSM)to

Denver (DEN)
Depart: 10/19/2026

One-way

Basic

From
$135
Seen: 20 hrs ago

Des Moines (DSM)to

Denver (DEN)
Depart: 10/17/2026

One-way

Basic

From
$135
Seen: 22 hrs ago

Des Moines (DSM)to

Denver (DEN)
Depart: 12/01/2026

One-way

Basic

From
$135
Seen: 16 hrs ago

Des Moines (DSM)to

Denver (DEN)
Depart: 10/29/2026

One-way

Basic

From
$135
Seen: 12 hrs ago

Des Moines (DSM)to

Denver (DEN)
Depart: 10/08/2026

One-way

Basic

From
$135
Seen: 8 hrs ago

Des Moines (DSM)to

Denver (DEN)
Depart: 12/03/2026

One-way

Basic

From
$135
Seen: 7 hrs ago

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Explore flights from Des Moines to Denver

Sep 2026
From$135*
Seen: 2 hrs ago
One Way/Basic
Oct 2026
From$135*
Seen: 16 hrs ago
One Way/Basic
Nov 2026
From$135*
Seen: 23 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $135
cmp-daily-histogram-bars-legend-max-price-aria-label $482
Displaying fares for September-2026
  • DSM–DEN, 09/10/2026: From $482
    10

    Thu

    SEP

  • DSM–DEN: cmp-view-offers-disclaimer. Find Offers
    11

    Fri

  • DSM–DEN, 09/12/2026: From $482
    12

    Sat

  • DSM–DEN: cmp-view-offers-disclaimer. Find Offers
    13

    Sun

  • DSM–DEN: cmp-view-offers-disclaimer. Find Offers
    14

    Mon

  • DSM–DEN: cmp-view-offers-disclaimer. Find Offers
    15

    Tue

  • DSM–DEN, 09/16/2026: From $309
    16

    Wed

  • DSM–DEN, 09/17/2026: From $309
    17

    Thu

  • DSM–DEN, 09/18/2026: From $309
    18

    Fri

  • DSM–DEN: cmp-view-offers-disclaimer. Find Offers
    19

    Sat

  • DSM–DEN, 09/20/2026: From $309
    20

    Sun

  • DSM–DEN: cmp-view-offers-disclaimer. Find Offers
    21

    Mon

  • DSM–DEN: cmp-view-offers-disclaimer. Find Offers
    22

    Tue

  • DSM–DEN, 09/23/2026: From $215
    23

    Wed

  • DSM–DEN, 09/24/2026: From $215
    24

    Thu

  • DSM–DEN: cmp-view-offers-disclaimer. Find Offers
    25

    Fri

  • DSM–DEN, 09/26/2026: From $215
    26

    Sat

  • DSM–DEN, 09/27/2026: From $225
    27

    Sun

  • DSM–DEN, 09/28/2026: From $215
    28

    Mon

  • DSM–DEN, 09/29/2026: From $215
    29

    Tue

  • DSM–DEN, 09/30/2026: From $135
    30

    Wed

  • DSM–DEN, 10/01/2026: From $135
    01

    Thu

    OCT

  • DSM–DEN, 10/02/2026: From $150
    02

    Fri

  • DSM–DEN: cmp-view-offers-disclaimer. Find Offers
    03

    Sat

  • DSM–DEN, 10/04/2026: From $195
    04

    Sun

  • DSM–DEN: cmp-view-offers-disclaimer. Find Offers
    05

    Mon

  • DSM–DEN: cmp-view-offers-disclaimer. Find Offers
    06

    Tue

  • DSM–DEN, 10/07/2026: From $145
    07

    Wed

  • DSM–DEN, 10/08/2026: From $135
    08

    Thu

  • DSM–DEN, 10/09/2026: From $148
    09

    Fri

    • Range$135-$482

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Des Moines Airport
    Arriving at:
    Denver International Airport
    Average flight time:
    1 hour 58 minutes
    Distance:
    589 miles

    Route Information

    69† Weekly flights
    • 1‡ Nonstop flight per day Monday through Friday
    • 1‡ Nonstop flight on Saturday
    • 1‡ Nonstop flight on Sunday

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    The average flight time from Des Moines to Denver is 1 hour 58 minutes.
    There are 69 weekly flights from Des Moines to Denver on Southwest Airlines.
    Yes, Southwest flies nonstop from Des Moines to Denver once per day from Monday through Friday.
    Yes, Southwest flies nonstop from Des Moines to Denver once per day on Saturdays and Sundays.
    To find the lowest fares by day and time to fly Des Moines to Denver with Southwest, check out our Low Fare Calendar.
    You can rent a car at Denver International Airport book yours with your flight.
    Yes! Flights from Des Moines to Denver—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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