Southwest® flights from Des Moines to Denver from $89

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Low fares from Des Moines to Denver

$

Des Moines (DSM)to

Denver (DEN)
Depart: 03/09/2026

One-way

Basic

From
$89
Seen: 32 minutes ago

Des Moines (DSM)to

Denver (DEN)
Depart: 04/13/2026

One-way

Basic

From
$90
Seen: 12 hrs ago

Des Moines (DSM)to

Denver (DEN)
Depart: 04/03/2026

One-way

Basic

From
$109
Seen: 10 hrs ago

Des Moines (DSM)to

Denver (DEN)
Depart: 02/23/2026

One-way

Basic

From
$109
Seen: 23 hrs ago

Des Moines (DSM)to

Denver (DEN)
Depart: 04/11/2026

One-way

Basic

From
$109
Seen: 10 hrs ago

Des Moines (DSM)to

Denver (DEN)
Depart: 03/28/2026

One-way

Basic

From
$109
Seen: 2 hrs ago

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Explore flights from Des Moines to Denver

*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

Flight Details

Departing from:
Des Moines Airport
Arriving at:
Denver International Airport
Average flight time:
1 hour 58 minutes
Distance:
589 miles

Route Information

69† Weekly flights
  • 1‡ Nonstop flight per day Monday through Friday
  • 1‡ Nonstop flight on Saturday
  • 1‡ Nonstop flight on Sunday

† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

Questions we hear the most

The average flight time from Des Moines to Denver is 1 hour 58 minutes.
There are 69 weekly flights from Des Moines to Denver on Southwest Airlines.
Yes, Southwest flies nonstop from Des Moines to Denver once per day from Monday through Friday.
Yes, Southwest flies nonstop from Des Moines to Denver once per day on Saturdays and Sundays.
To find the lowest fares by day and time to fly Des Moines to Denver with Southwest, check out our Low Fare Calendar.
You can rent a car at Denver International Airport book yours with your flight.
Yes! Flights from Des Moines to Denver—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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