Southwest® flights from Des Moines to Indianapolis from $199

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Low fares from Des Moines to Indianapolis

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Des Moines (DSM)to

Indianapolis (IND)
Depart: 11/01/2026

One-way

Basic

From
$199
Seen: 6 hrs ago

Des Moines (DSM)to

Indianapolis (IND)
Depart: 10/24/2026

One-way

Basic

From
$225
Seen: 2 hrs ago

Des Moines (DSM)to

Indianapolis (IND)
Depart: 11/01/2026

One-way

Choice

From
$234
Seen: 6 hrs ago

Des Moines (DSM)to

Indianapolis (IND)
Depart: 10/21/2026

One-way

Basic

From
$245
Seen: 7 hrs ago

Des Moines (DSM)to

Indianapolis (IND)
Depart: 10/24/2026

One-way

Choice

From
$260
Seen: 2 hrs ago

Des Moines (DSM)to

Indianapolis (IND)
Depart: 10/21/2026

One-way

Choice

From
$280
Seen: 7 hrs ago

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Explore flights from Des Moines to Indianapolis

Oct 2026
From$225*
Seen: 2 hrs ago
One Way/Basic
Nov 2026
From$199*
Seen: 6 hrs ago
One Way/Basic
Dec 2026
No result for this month.
cmp-daily-histogram-bars-legend-min-price-aria-label $199
cmp-daily-histogram-bars-legend-max-price-aria-label $399
Displaying fares for October-2026
  • DSM–IND, 10/04/2026: From $399
    04

    Sun

    OCT

  • DSM–IND, 10/05/2026: From $399
    05

    Mon

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    06

    Tue

  • DSM–IND, 10/07/2026: From $399
    07

    Wed

  • DSM–IND, 10/08/2026: From $399
    08

    Thu

  • DSM–IND, 10/09/2026: From $399
    09

    Fri

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    10

    Sat

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    11

    Sun

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    12

    Mon

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    13

    Tue

  • DSM–IND, 10/14/2026: From $334
    14

    Wed

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    15

    Thu

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    16

    Fri

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    17

    Sat

  • DSM–IND, 10/18/2026: From $369
    18

    Sun

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    19

    Mon

  • DSM–IND: cmp-view-offers-disclaimer. Find Offers
    20

    Tue

  • DSM–IND, 10/21/2026: From $245
    21

    Wed

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    22

    Thu

  • DSM–IND: cmp-view-offers-disclaimer. Find Offers
    23

    Fri

  • DSM–IND, 10/24/2026: From $225
    24

    Sat

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    25

    Sun

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    26

    Mon

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    27

    Tue

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    28

    Wed

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    29

    Thu

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    30

    Fri

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    31

    Sat

  • DSM–IND, 11/01/2026: From $199
    01

    Sun

    NOV

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    02

    Mon

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    03

    Tue

    • Range$199-$399

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Des Moines Airport
    Arriving at:
    Indianapolis International Airport
    Distance:
    407 miles

    Route Information

    36† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 36 weekly flights from Des Moines to Indianapolis on Southwest Airlines.
    To find the lowest fares by day and time to fly Des Moines to Indianapolis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Indianapolis International Airport book yours with your flight.
    Yes! Flights from Des Moines to Indianapolis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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