Southwest® flights from Knoxville to Memphis from $140
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1 Passenger
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today
Low fares from Knoxville to Memphis
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$
Knoxville (TYS)to
Memphis (MEM)
Depart: 04/28/2026
One-way
Basic
From
$140
Low fares from Knoxville to Memphis
$
Knoxville (TYS)to
Memphis (MEM)
Depart: 04/28/2026
One-way
Basic
From
$140
Seen: 2 hrs ago
Knoxville (TYS)to
Memphis (MEM)
Depart: 03/30/2026
One-way
Basic
From
$150
Seen: 10 hrs ago
Knoxville (TYS)to
Memphis (MEM)
Depart: 03/16/2026
One-way
Basic
From
$150
Seen: 9 hrs ago
Knoxville (TYS)to
Memphis (MEM)
Depart: 04/28/2026
One-way
Choice
From
$170
Seen: 2 hrs ago
Knoxville (TYS)to
Memphis (MEM)
Depart: 03/16/2026
One-way
Choice
From
$180
Seen: 9 hrs ago
Knoxville (TYS)to
Memphis (MEM)
Depart: 03/30/2026
One-way
Choice
From
$180
Seen: 10 hrs ago
Explore flights from Knoxville to Memphis
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Flight Details
Departing from:
Mc Ghee Tyson Airport
Arriving at:
Memphis International Airport
Distance:
342 miles
Route Information
42† Weekly flights
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
There are 42 weekly flights from Knoxville to Memphis on Southwest Airlines.
To find the lowest fares by day and time to fly Knoxville to Memphis with Southwest, check out our Low Fare Calendar.
You can rent a car at Memphis International Airport book yours with your flight.
Yes! Flights from Knoxville to Memphis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.