Southwest® flights from Knoxville to Las Vegas from $160

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Low fares from Knoxville to Las Vegas

$

Knoxville (TYS)to

Las Vegas (LAS)
Depart: 10/22/2026

One-way

Basic

From
$160

Low fares from Knoxville to Las Vegas

$

Knoxville (TYS)to

Las Vegas (LAS)
Depart: 10/22/2026

One-way

Basic

From
$160
Seen: 14 hrs ago

Knoxville (TYS)to

Las Vegas (LAS)
Depart: 11/04/2026

One-way

Basic

From
$160
Seen: 14 hrs ago

Knoxville (TYS)to

Las Vegas (LAS)
Depart: 10/24/2026

One-way

Basic

From
$160
Seen: 13 hrs ago

Knoxville (TYS)to

Las Vegas (LAS)
Depart: 11/02/2026

One-way

Basic

From
$160
Seen: 18 hrs ago

Knoxville (TYS)to

Las Vegas (LAS)
Depart: 11/13/2026

One-way

Basic

From
$184
Seen: 18 hrs ago

Knoxville (TYS)to

Las Vegas (LAS)
Depart: 10/23/2026

One-way

Basic

From
$184
Seen: 14 hrs ago

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Explore flights from Knoxville to Las Vegas

Sep 2026
From$402*
Seen: 17 hrs ago
One Way/Basic
Oct 2026
From$160*
Seen: 14 hrs ago
One Way/Basic
Nov 2026
From$160*
Seen: 18 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $249
cmp-daily-histogram-bars-legend-max-price-aria-label $474
Displaying fares for September-2026
  • TYS–LAS, 09/21/2026: From $469
    21

    Mon

    SEP

  • TYS–LAS: cmp-view-offers-disclaimer. Find Offers
    22

    Tue

  • TYS–LAS, 09/23/2026: From $469
    23

    Wed

  • TYS–LAS, 09/24/2026: From $469
    24

    Thu

  • TYS–LAS: cmp-view-offers-disclaimer. Find Offers
    25

    Fri

  • TYS–LAS, 09/26/2026: From $402
    26

    Sat

  • TYS–LAS: cmp-view-offers-disclaimer. Find Offers
    27

    Sun

  • TYS–LAS, 09/28/2026: From $469
    28

    Mon

  • TYS–LAS: cmp-view-offers-disclaimer. Find Offers
    29

    Tue

  • TYS–LAS, 09/30/2026: From $424
    30

    Wed

  • TYS–LAS, 10/01/2026: From $474
    01

    Thu

    OCT

  • TYS–LAS, 10/02/2026: From $474
    02

    Fri

  • TYS–LAS, 10/03/2026: From $424
    03

    Sat

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    04

    Sun

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    05

    Mon

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    06

    Tue

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    07

    Wed

  • TYS–LAS, 10/08/2026: From $319
    08

    Thu

  • TYS–LAS, 10/09/2026: From $420
    09

    Fri

  • TYS–LAS, 10/10/2026: From $319
    10

    Sat

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    11

    Sun

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    12

    Mon

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    13

    Tue

  • TYS–LAS, 10/14/2026: From $260
    14

    Wed

  • TYS–LAS, 10/15/2026: From $249
    15

    Thu

  • TYS–LAS, 10/16/2026: From $249
    16

    Fri

  • TYS–LAS, 10/17/2026: From $300
    17

    Sat

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    18

    Sun

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    19

    Mon

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    20

    Tue

    • Range$249-$474

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Mc Ghee Tyson Airport
    Arriving at:
    McCarran International Airport
    Distance:
    1739 miles

    Route Information

    80† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 80 weekly flights from Knoxville to Las Vegas on Southwest Airlines.
    To find the lowest fares by day and time to fly Knoxville to Las Vegas with Southwest, check out our Low Fare Calendar.
    You can rent a car at McCarran International Airport book yours with your flight.
    Yes! Flights from Knoxville to Las Vegas—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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