Southwest® flights from Knoxville to Greenville-Spartanburg

Promo Code

Low fares from Knoxville to Greenville-Spartanburg

$

Low fares from Knoxville to Greenville-Spartanburg

$
Two happy travelers riding a scooter at sunset, promoting low-fare flights.

Looking for more low-fare flights?

Check out the Low Fare Calendar to find a fare that works for you. Just choose the month you want to depart and return, and we’ll show you the best fares available.

Find low fares

Explore flights from Knoxville to Greenville-Spartanburg

Flight Details

Departing from:
Mc Ghee Tyson Airport
Arriving at:
Greenville-Spartanburg International Airport
Distance:
118 miles

Route Information

14 Weekly flights

† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

Questions we hear the most

There are 14 weekly flights from Knoxville to Greenville-Spartanburg on Southwest Airlines.
To find the lowest fares by day and time to fly Knoxville to Greenville-Spartanburg with Southwest, check out our Low Fare Calendar.
You can rent a car at Greenville-Spartanburg International Airport book yours with your flight.
Yes! Flights from Knoxville to Greenville-Spartanburg—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.

Popular Flights from Knoxville