Southwest® flights from Des Moines to West Palm Beach from $242

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Low fares from Des Moines to West Palm Beach

$

Des Moines (DSM)to

West Palm Beach (PBI)
Depart: 04/10/2026

One-way

Basic

From
$242
Seen: 10 hrs ago

Des Moines (DSM)to

West Palm Beach (PBI)
Depart: 03/28/2026

One-way

Basic

From
$249
Seen: 9 hrs ago

Des Moines (DSM)to

West Palm Beach (PBI)
Depart: 04/09/2026

One-way

Basic

From
$255
Seen: 4 hrs ago

Des Moines (DSM)to

West Palm Beach (PBI)
Depart: 03/17/2026

One-way

Basic

From
$265
Seen: 23 hrs ago

Des Moines (DSM)to

West Palm Beach (PBI)
Depart: 06/04/2026

One-way

Basic

From
$278
Seen: 11 hrs ago

Des Moines (DSM)to

West Palm Beach (PBI)
Depart: 03/10/2026

One-way

Basic

From
$279
Seen: 20 hrs ago

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Explore flights from Des Moines to West Palm Beach

*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

Flight Details

Departing from:
Des Moines Airport
Arriving at:
Palm Beach International Airport
Distance:
1282 miles

Route Information

28† Weekly flights

† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

Questions we hear the most

There are 28 weekly flights from Des Moines to West Palm Beach on Southwest Airlines.
To find the lowest fares by day and time to fly Des Moines to West Palm Beach with Southwest, check out our Low Fare Calendar.
You can rent a car at Palm Beach International Airport book yours with your flight.
Yes! Flights from Des Moines to West Palm Beach—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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