Southwest® flights from Knoxville to Denver from $135

Promo Code

Low fares from Knoxville to Denver

$

Knoxville (TYS)to

Denver (DEN)
Depart: 08/12/2026

One-way

Basic

From
$135

Low fares from Knoxville to Denver

$

Knoxville (TYS)to

Denver (DEN)
Depart: 04/11/2026

One-way

Basic

From
$135
Seen: 9 hrs ago

Knoxville (TYS)to

Denver (DEN)
Depart: 04/15/2026

One-way

Basic

From
$144
Seen: 3 hrs ago

Knoxville (TYS)to

Denver (DEN)
Depart: 06/10/2026

One-way

Basic

From
$144
Seen: 12 hrs ago

Knoxville (TYS)to

Denver (DEN)
Depart: 05/27/2026

One-way

Basic

From
$144
Seen: 12 hrs ago

Knoxville (TYS)to

Denver (DEN)
Depart: 04/21/2026

One-way

Basic

From
$144
Seen: 5 hrs ago

Knoxville (TYS)to

Denver (DEN)
Depart: 05/12/2026

One-way

Basic

From
$144
Seen: 3 hrs ago

Looking for more low-fare flights?

Check out the Low Fare Calendar to find a fare that works for you. Just choose the month you want to depart and return, and we’ll show you the best fares available.

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Explore flights from Knoxville to Denver

Mar 2026
From$170*
Seen: 3 hrs ago
One Way/Basic
Apr 2026
From$135*
Seen: 9 hrs ago
One Way/Basic
May 2026
From$144*
Seen: 3 hrs ago
One Way/Basic
$135
$349
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    • Range$135-$349

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Mc Ghee Tyson Airport
    Arriving at:
    Denver International Airport
    Average flight time:
    3 hours 22 minutes
    Distance:
    1162 miles

    Route Information

    73† Weekly flights
    • 1‡ Nonstop flight on Saturday
    • 1‡ Nonstop flight on Sunday

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    The average flight time from Knoxville to Denver is 3 hours 22 minutes.
    There are 73 weekly flights from Knoxville to Denver on Southwest Airlines.
    Yes, Southwest flies nonstop from Knoxville to Denver once per day on Saturdays and Sundays.
    To find the lowest fares by day and time to fly Knoxville to Denver with Southwest, check out our Low Fare Calendar.
    You can rent a car at Denver International Airport book yours with your flight.
    Yes! Flights from Knoxville to Denver—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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