Chicago (Midway) (MDW)to
Des Moines (DSM)Denver (DEN)to
Des Moines (DSM)Houston (Hobby) (HOU)to
Des Moines (DSM)Phoenix (PHX)to
Des Moines (DSM)San Diego (SAN)to
Des Moines (DSM)Baltimore/Washington (BWI)to
Des Moines (DSM)Las Vegas (LAS)to
Des Moines (DSM)Austin (AUS)to
Des Moines (DSM)St. Louis (STL)to
Des Moines (DSM)Los Angeles (LAX)to
Des Moines (DSM)Dallas (Love Field) (DAL)to
Des Moines (DSM)Atlanta (ATL)to
Des Moines (DSM)Nashville (BNA)to
Des Moines (DSM)New York (LaGuardia) (LGA)to
Des Moines (DSM)Tampa (TPA)to
Des Moines (DSM)Orlando (MCO)to
Des Moines (DSM)Sacramento (SMF)to
Des Moines (DSM)Oakland (OAK)to
Des Moines (DSM)San Jose, CA (SJC)to
Des Moines (DSM)Ontario/LA (ONT)to
Des Moines (DSM)*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.
Set down smack-dab in the middle of Iowa, Des Moines offers visitors a chance to see what the Midwest is all about. Rich in history while a burgeoning tourism hot spot, Iowa’s fast-growing capital city is a perfect destination for a long weekend or longer stays. After all, it’s quite cozy there—you might find you want to linger a while after your arrival in the Hawkeye State.
While its name might translate to “of the Monks,” the Des Moines of today is no place for quiet retreat. This urban oasis in the Great Plains is a bustling city of hundreds of thousands of Iowans and home to an array of natural, cultural, and culinary delights. The city’s centerpiece is the stunning State Capitol building, the only five-domed capitol in the United States. This stately 19th-century structure is not only home to the state’s legislature, but also the annual World Food Prize ceremony that draws visitors from all over the world.
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 10/1/2025 and 10/31/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 10/1/2025 and 10/31/2025.
St. Louis (STL)to
One-way
Basic
Chicago (Midway) (MDW)to
One-way
Basic
Denver (DEN)to
One-way
Basic
Phoenix (PHX)to
One-way
Basic
Houston (Hobby) (HOU)to
One-way
Basic
Philadelphia (PHL)to
One-way
Basic
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