Southwest® flights to Knoxville starting at $120

Promo Code

Popular flights to Knoxville on Southwest Airlines

$

Baltimore/Washington (BWI)to

Knoxville (TYS)
Depart: 01/16/2027
From
$120
One-way
Basic

Nashville (BNA)to

Knoxville (TYS)
Depart: 01/12/2027
From
$137
One-way
Basic

Hartford/Springfield (BDL)to

Knoxville (TYS)
Depart: 12/08/2026
From
$146
One-way
Basic

Dallas-Love Field (DAL)to

Knoxville (TYS)
Depart: 02/03/2027
From
$150
One-way
Basic

Cleveland (CLE)to

Knoxville (TYS)
Depart: 12/09/2026
From
$153
One-way
Basic

Indianapolis (IND)to

Knoxville (TYS)
Depart: 02/10/2027
From
$153
One-way
Basic

Little Rock (LIT)to

Knoxville (TYS)
Depart: 12/15/2026
From
$153
One-way
Basic

Charleston (CHS)to

Knoxville (TYS)
Depart: 02/16/2027
From
$160
One-way
Basic

Greenville-Spartanburg (GSP)to

Knoxville (TYS)
Depart: 12/15/2026
From
$160
One-way
Basic

Austin (AUS)to

Knoxville (TYS)
Depart: 12/15/2026
From
$164
One-way
Basic

Washington D.C. Reagan National (DCA)to

Knoxville (TYS)
Depart: 12/16/2026
From
$164
One-way
Basic

Fort Lauderdale (FLL)to

Knoxville (TYS)
Depart: 01/14/2027
From
$166
One-way
Basic

Jacksonville (JAX)to

Knoxville (TYS)
Depart: 12/24/2026
From
$166
One-way
Basic

Houston Hobby (HOU)to

Knoxville (TYS)
Depart: 01/06/2027
From
$169
One-way
Basic

Boston (BOS)to

Knoxville (TYS)
Depart: 12/07/2026
From
$172
One-way
Basic

Columbus (CMH)to

Knoxville (TYS)
Depart: 12/08/2026
From
$173
One-way
Basic

Grand Rapids (GRR)to

Knoxville (TYS)
Depart: 01/07/2027
From
$173
One-way
Basic

Las Vegas (LAS)to

Knoxville (TYS)
Depart: 12/12/2026
From
$176
One-way
Basic

Denver (DEN)to

Knoxville (TYS)
Depart: 01/16/2027
From
$177
One-way
Basic

Buffalo/Niagara Falls (BUF)to

Knoxville (TYS)
Depart: 02/25/2027
From
$180
One-way
Basic
*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

Popular flights to Knoxville on Southwest Airlines

$

Baltimore/Washington (BWI)to

Knoxville (TYS)
Depart: 12/08/2026
From
$120
Seen: 18 hrs ago
One-way
Basic

Nashville (BNA)to

Knoxville (TYS)
Depart: 12/08/2026
From
$137
Seen: 2 hrs ago
One-way
Basic

Hartford/Springfield (BDL)to

Knoxville (TYS)
Depart: 12/08/2026
From
$146
Seen: 4 hrs ago
One-way
Basic

Cleveland (CLE)to

Knoxville (TYS)
Depart: 12/09/2026
From
$153
Seen: 3 hrs ago
One-way
Basic

Austin (AUS)to

Knoxville (TYS)
Depart: 12/08/2026
From
$164
Seen: 5 hrs ago
One-way
Basic

Boston (BOS)to

Knoxville (TYS)
Depart: 12/07/2026
From
$172
Seen: 2 hrs ago
One-way
Basic

Columbus (CMH)to

Knoxville (TYS)
Depart: 12/08/2026
From
$173
Seen: 13 hrs ago
One-way
Basic

Atlanta (ATL)to

Knoxville (TYS)
Depart: 11/27/2026
From
$185
Seen: 12 hrs ago
One-way
Basic

Birmingham (BHM)to

Knoxville (TYS)
Depart: 12/11/2026
From
$195
Seen: 17 hrs ago
One-way
Basic

Albuquerque (ABQ)to

Knoxville (TYS)
Depart: 12/09/2026
From
$203
Seen: 23 hrs ago
One-way
Basic

Boise (BOI)to

Knoxville (TYS)
Depart: 12/08/2026
From
$209
Seen: 15 hrs ago
One-way
Basic

Buffalo/Niagara Falls (BUF)to

Knoxville (TYS)
Depart: 12/10/2026
From
$219
Seen: 20 hrs ago
One-way
Basic

Charlotte (CLT)to

Knoxville (TYS)
Depart: 11/14/2026
From
$244
Seen: 1 hour ago
One-way
Basic

Albany (ALB)to

Knoxville (TYS)
Depart: 12/03/2026
From
$259
Seen: 8 hrs ago
One-way
Basic

Colorado Springs (COS)to

Knoxville (TYS)
Depart: 11/28/2026
From
$262
Seen: 10 hrs ago
One-way
Basic

Amarillo (AMA)to

Knoxville (TYS)
Depart: 11/14/2026
From
$274
Seen: 19 hrs ago
One-way
Basic

Bozeman (BZN)to

Knoxville (TYS)
Depart: 12/06/2026
From
$284
Seen: 2 hrs ago
One-way
Basic

Burbank (BUR)to

Knoxville (TYS)
Depart: 11/25/2026
From
$321
Seen: 3 hrs ago
One-way
Basic

Charleston (CHS)to

Knoxville (TYS)
Depart: 11/16/2026
From
$344
Seen: 11 hrs ago
One-way
Choice

Cancun (CUN)to

Knoxville (TYS)
Depart: 12/02/2026
From
$356
Seen: 18 hrs ago
One-way
Basic
*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

Discover Knoxville with Southwest Airlines

Book your next flight to Knoxville with Southwest Airlines and discover why East Tennessee is a destination filled with mountain beauty, vibrant culture, and Southern charm. Learn more about the Southwest® Experience and start planning your Knoxville getaway today.


Flying to Knoxville with Southwest Airlines

  • Enjoy easy access to East Tennessee with flights landing at Knoxville’s McGhee Tyson Airport (TYS), just minutes from downtown.
  • Arrive stress-free with Southwest’s convenient service and famously friendly hospitality.
  • With low fares and no hidden fees, Southwest makes getting to Knoxville as comfortable as the Southern charm that greets you.

Best Food & Drink in Knoxville

  • Start your day with a local favorite of biscuits smothered in sausage gravy or a made-from-scratch donut from a hometown bakery.
  • Enjoy a farm-to-table dinner at Market Square or take a short drive to Pigeon Forge for classic Southern comfort food and live dinner shows.
  • Taste Appalachian flavors inspired by the region’s mountain heritage and family recipes passed down for generations.

Find cheap flights to Knoxville

$

Baltimore/Washington (BWI)to

Knoxville (TYS)
Depart: 01/16/2027

One-way

Basic

From
$120
Seen: 18 hrs ago

Nashville (BNA)to

Knoxville (TYS)
Depart: 01/12/2027

One-way

Basic

From
$137
Seen: 10 hrs ago

Hartford/Springfield (BDL)to

Knoxville (TYS)
Depart: 12/08/2026

One-way

Basic

From
$146
Seen: 4 hrs ago

Dallas-Love Field (DAL)to

Knoxville (TYS)
Depart: 02/03/2027

One-way

Basic

From
$150
Seen: 11 hrs ago

Cleveland (CLE)to

Knoxville (TYS)
Depart: 12/09/2026

One-way

Basic

From
$153
Seen: 3 hrs ago

Indianapolis (IND)to

Knoxville (TYS)
Depart: 02/10/2027

One-way

Basic

From
$153
Seen: 23 hrs ago

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More Southwest flights to Knoxville