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Southwest® flights to Knoxville starting at $94

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Popular flights to Knoxville on Southwest Airlines

$

Baltimore/Washington (BWI)to

Knoxville (TYS)
Depart: 07/28/2026
From
$94
One-way
Basic

Washington, D.C. (Reagan National) (DCA)to

Knoxville (TYS)
Depart: 07/14/2026
From
$104
One-way
Basic

Nashville (BNA)to

Knoxville (TYS)
Depart: 09/01/2026
From
$114
One-way
Basic

Dallas (Love Field) (DAL)to

Knoxville (TYS)
Depart: 11/11/2026
From
$122
One-way
Basic

Hartford/Springfield (BDL)to

Knoxville (TYS)
Depart: 05/27/2026
From
$131
One-way
Basic

Albuquerque (ABQ)to

Knoxville (TYS)
Depart: 06/30/2026
From
$133
One-way
Basic

Panama City Beach, FL (ECP)to

Knoxville (TYS)
Depart: 06/24/2026
From
$135
One-way
Basic

Atlanta (ATL)to

Knoxville (TYS)
Depart: 08/14/2026
From
$140
One-way
Basic

Jacksonville (JAX)to

Knoxville (TYS)
Depart: 06/10/2026
From
$140
One-way
Basic

Houston (Hobby) (HOU)to

Knoxville (TYS)
Depart: 08/03/2026
From
$145
One-way
Basic

Indianapolis (IND)to

Knoxville (TYS)
Depart: 08/12/2026
From
$146
One-way
Basic

Albany (ALB)to

Knoxville (TYS)
Depart: 06/16/2026
From
$146
One-way
Basic

Austin (AUS)to

Knoxville (TYS)
Depart: 10/20/2026
From
$146
One-way
Basic

Boston (BOS)to

Knoxville (TYS)
Depart: 06/23/2026
From
$147
One-way
Basic

Charleston (CHS)to

Knoxville (TYS)
Depart: 06/09/2026
From
$148
One-way
Basic

Cleveland (CLE)to

Knoxville (TYS)
Depart: 06/30/2026
From
$148
One-way
Basic

Fort Lauderdale (FLL)to

Knoxville (TYS)
Depart: 06/10/2026
From
$148
One-way
Basic

Birmingham (BHM)to

Knoxville (TYS)
Depart: 07/07/2026
From
$150
One-way
Basic

Columbus (CMH)to

Knoxville (TYS)
Depart: 07/21/2026
From
$150
One-way
Basic

Detroit (DTW)to

Knoxville (TYS)
Depart: 06/09/2026
From
$150
One-way
Basic

*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

Popular flights to Knoxville on Southwest Airlines

$

Baltimore/Washington (BWI)to

Knoxville (TYS)
Depart: 06/10/2026
From
$122
Seen: 16 hrs ago
One-way
Basic

Hartford/Springfield (BDL)to

Knoxville (TYS)
Depart: 05/27/2026
From
$131
Seen: 15 hrs ago
One-way
Basic

Nashville (BNA)to

Knoxville (TYS)
Depart: 06/14/2026
From
$141
Seen: 12 hrs ago
One-way
Basic

Charleston (CHS)to

Knoxville (TYS)
Depart: 06/09/2026
From
$148
Seen: 10 hrs ago
One-way
Basic

Austin (AUS)to

Knoxville (TYS)
Depart: 06/10/2026
From
$151
Seen: 7 hrs ago
One-way
Basic

Albany (ALB)to

Knoxville (TYS)
Depart: 06/08/2026
From
$156
Seen: 9 hrs ago
One-way
Basic

Atlanta (ATL)to

Knoxville (TYS)
Depart: 06/11/2026
From
$160
Seen: 6 hrs ago
One-way
Basic

Birmingham (BHM)to

Knoxville (TYS)
Depart: 06/11/2026
From
$164
Seen: 14 hrs ago
One-way
Basic

Charlotte (CLT)to

Knoxville (TYS)
Depart: 06/08/2026
From
$166
Seen: 18 hrs ago
One-way
Basic

Buffalo/Niagara Falls (BUF)to

Knoxville (TYS)
Depart: 05/24/2026
From
$179
Seen: 10 hrs ago
One-way
Basic

Cleveland (CLE)to

Knoxville (TYS)
Depart: 06/10/2026
From
$183
Seen: 19 hrs ago
One-way
Basic

Boston (BOS)to

Knoxville (TYS)
Depart: 06/06/2026
From
$209
Seen: 13 hrs ago
One-way
Basic

Albuquerque (ABQ)to

Knoxville (TYS)
Depart: 06/09/2026
From
$211
Seen: 10 hrs ago
One-way
Basic

Colorado Springs (COS)to

Knoxville (TYS)
Depart: 05/16/2026
From
$212
Seen: 8 hrs ago
One-way
Basic

Columbus (CMH)to

Knoxville (TYS)
Depart: 06/14/2026
From
$222
Seen: 17 hrs ago
One-way
Basic

Amarillo (AMA)to

Knoxville (TYS)
Depart: 06/10/2026
From
$227
Seen: 9 hrs ago
One-way
Basic

Bozeman (BZN)to

Knoxville (TYS)
Depart: 06/08/2026
From
$231
Seen: 12 hrs ago
One-way
Basic

Boise (BOI)to

Knoxville (TYS)
Depart: 06/09/2026
From
$269
Seen: 5 hrs ago
One-way
Basic

Burbank (BUR)to

Knoxville (TYS)
Depart: 05/30/2026
From
$289
Seen: 11 hrs ago
One-way
Basic

Anchorage (ANC)to

Knoxville (TYS)
Depart: 05/15/2026
From
$592
Seen: 13 hrs ago
One-way
Choice

*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

Discover Knoxville with Southwest Airlines

Book your next flight to Knoxville with Southwest Airlines and discover why East Tennessee is a destination filled with mountain beauty, vibrant culture, and Southern charm. Learn more about the Southwest® Experience and start planning your Knoxville getaway today.


Flying to Knoxville with Southwest Airlines

  • Enjoy easy access to East Tennessee with flights landing at Knoxville’s McGhee Tyson Airport (TYS), just minutes from downtown.
  • Arrive stress-free with Southwest’s convenient service and famously friendly hospitality.
  • With low fares and no hidden fees, Southwest makes getting to Knoxville as comfortable as the Southern charm that greets you.

Best Food & Drink in Knoxville

  • Start your day with a local favorite of biscuits smothered in sausage gravy or a made-from-scratch donut from a hometown bakery.
  • Enjoy a farm-to-table dinner at Market Square or take a short drive to Pigeon Forge for classic Southern comfort food and live dinner shows.
  • Taste Appalachian flavors inspired by the region’s mountain heritage and family recipes passed down for generations.

Find cheap flights to Knoxville

$

Baltimore/Washington (BWI)to

Knoxville (TYS)
Depart: 07/28/2026

One-way

Basic

From
$94
Seen: 16 hrs ago

Washington, D.C. (Reagan National) (DCA)to

Knoxville (TYS)
Depart: 07/14/2026

One-way

Basic

From
$104
Seen: 14 hrs ago

Orlando (MCO)to

Knoxville (TYS)
Depart: 06/16/2026

One-way

Basic

From
$106
Seen: 11 hrs ago

Nashville (BNA)to

Knoxville (TYS)
Depart: 07/07/2026

One-way

Basic

From
$114
Seen: 1 hour ago

Dallas (Love Field) (DAL)to

Knoxville (TYS)
Depart: 06/30/2026

One-way

Basic

From
$122
Seen: 17 hrs ago

Hartford/Springfield (BDL)to

Knoxville (TYS)
Depart: 05/27/2026

One-way

Basic

From
$131
Seen: 15 hrs ago

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More Southwest flights to Knoxville