Southwest® flights to Knoxville starting at $82
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Popular flights to Knoxville on Southwest Airlines
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$
Baltimore/Washington (BWI)to
Knoxville (TYS)Depart: 03/11/2026
From
$82
One-way
Basic
Orlando (MCO)to
Knoxville (TYS)Depart: 03/11/2026
From
$100
One-way
Basic
Hartford/Springfield (BDL)to
Knoxville (TYS)Depart: 04/08/2026
From
$101
One-way
Basic
Jacksonville (JAX)to
Knoxville (TYS)Depart: 03/11/2026
From
$101
One-way
Basic
Chicago (Midway) (MDW)to
Knoxville (TYS)Depart: 03/17/2026
From
$105
One-way
Basic
Milwaukee (MKE)to
Knoxville (TYS)Depart: 05/12/2026
From
$105
One-way
Basic
Albuquerque (ABQ)to
Knoxville (TYS)Depart: 04/15/2026
From
$108
One-way
Basic
Atlanta (ATL)to
Knoxville (TYS)Depart: 03/10/2026
From
$110
One-way
Basic
Dallas (Love Field) (DAL)to
Knoxville (TYS)Depart: 03/06/2026
From
$116
One-way
Basic
Nashville (BNA)to
Knoxville (TYS)Depart: 04/14/2026
From
$119
One-way
Basic
Colorado Springs (COS)to
Knoxville (TYS)Depart: 04/22/2026
From
$125
One-way
Basic
Denver (DEN)to
Knoxville (TYS)Depart: 03/17/2026
From
$125
One-way
Basic
Jackson (JAN)to
Knoxville (TYS)Depart: 03/10/2026
From
$133
One-way
Basic
Cleveland (CLE)to
Knoxville (TYS)Depart: 03/24/2026
From
$134
One-way
Basic
Washington, D.C. (Reagan National) (DCA)to
Knoxville (TYS)Depart: 09/02/2026
From
$139
One-way
Basic
Houston (Hobby) (HOU)to
Knoxville (TYS)Depart: 06/03/2026
From
$149
One-way
Basic
Columbus (CMH)to
Knoxville (TYS)Depart: 03/25/2026
From
$154
One-way
Basic
Detroit (DTW)to
Knoxville (TYS)Depart: 03/17/2026
From
$159
One-way
Basic
Austin (AUS)to
Knoxville (TYS)Depart: 03/23/2026
From
$160
One-way
Basic
Panama City Beach, FL (ECP)to
Knoxville (TYS)Depart: 03/29/2026
From
$160
One-way
Basic
*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.
Popular flights to Knoxville on Southwest Airlines
flight_takeoff
flight_land
$
Houston (Hobby) (HOU)to
Knoxville (TYS)Depart: 01/10/2026
From
$154
Seen: 22 hrs ago
One-way
Basic
*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.
Discover Knoxville with Southwest Airlines
Book your next flight to Knoxville with Southwest Airlines and discover why East Tennessee is a destination filled with mountain beauty, vibrant culture, and Southern charm. Learn more about the Southwest® Experience and start planning your Knoxville getaway today.
Flying to Knoxville with Southwest Airlines
- Enjoy easy access to East Tennessee with flights landing at Knoxville’s McGhee Tyson Airport (TYS), just minutes from downtown.
- Arrive stress-free with Southwest’s convenient service and famously friendly hospitality.
- With low fares and no hidden fees, Southwest makes getting to Knoxville as comfortable as the Southern charm that greets you.
Best Food & Drink in Knoxville
- Start your day with a local favorite of biscuits smothered in sausage gravy or a made-from-scratch donut from a hometown bakery.
- Enjoy a farm-to-table dinner at Market Square or take a short drive to Pigeon Forge for classic Southern comfort food and live dinner shows.
- Taste Appalachian flavors inspired by the region’s mountain heritage and family recipes passed down for generations.
Find cheap flights to Knoxville
flight_takeoff
flight_land
$
Baltimore/Washington (BWI)to
Knoxville (TYS)
Depart: 03/11/2026
One-way
Basic
From
$82
Seen: 15 hrs ago
Orlando (MCO)to
Knoxville (TYS)
Depart: 03/11/2026
One-way
Basic
From
$100
Seen: 6 hrs ago
Jacksonville (JAX)to
Knoxville (TYS)
Depart: 03/11/2026
One-way
Basic
From
$101
Seen: 20 hrs ago
Chicago (Midway) (MDW)to
Knoxville (TYS)
Depart: 03/17/2026
One-way
Basic
From
$105
Seen: 13 hrs ago
San Antonio (SAT)to
Knoxville (TYS)
Depart: 03/17/2026
One-way
Basic
From
$109
Seen: 6 hrs ago
Atlanta (ATL)to
Knoxville (TYS)
Depart: 03/10/2026
One-way
Basic
From
$110
Seen: 21 hrs ago
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