Southwest® flights to Knoxville starting at $109

Promo Code
Knoxville

Visit Knoxville


Book your flight to Knoxville and explore mountain views, live music, and nearby adventures in Gatlinburg and Pigeon Forge.

Flights available to book today. Service starts March 5, 2026.

Find flights

Popular flights to Knoxville on Southwest Airlines

$

Washington, D.C. (Reagan National) (DCA)to

Knoxville (TYS)
Depart: 03/11/2026
From
$105
One-way
Basic

Chicago (Midway) (MDW)to

Knoxville (TYS)
Depart: 03/10/2026
From
$105
One-way
Basic

Albuquerque (ABQ)to

Knoxville (TYS)
Depart: 03/17/2026
From
$108
One-way
Basic

Baltimore/Washington (BWI)to

Knoxville (TYS)
Depart: 03/10/2026
From
$109
One-way
Basic

Atlanta (ATL)to

Knoxville (TYS)
Depart: 04/26/2026
From
$110
One-way
Basic

Houston (Hobby) (HOU)to

Knoxville (TYS)
Depart: 06/24/2026
From
$115
One-way
Basic

Orlando (MCO)to

Knoxville (TYS)
Depart: 03/11/2026
From
$119
One-way
Basic

Nashville (BNA)to

Knoxville (TYS)
Depart: 03/19/2026
From
$119
One-way
Basic

Colorado Springs (COS)to

Knoxville (TYS)
Depart: 04/14/2026
From
$125
One-way
Basic

Denver (DEN)to

Knoxville (TYS)
Depart: 04/05/2026
From
$125
One-way
Basic

Jacksonville (JAX)to

Knoxville (TYS)
Depart: 05/06/2026
From
$130
One-way
Basic

Cleveland (CLE)to

Knoxville (TYS)
Depart: 04/25/2026
From
$134
One-way
Basic

Kansas City (MCI)to

Knoxville (TYS)
Depart: 06/16/2026
From
$134
One-way
Basic

Dallas (Love Field) (DAL)to

Knoxville (TYS)
Depart: 03/12/2026
From
$139
One-way
Basic

Boston (BOS)to

Knoxville (TYS)
Depart: 06/17/2026
From
$140
One-way
Basic

Panama City Beach, FL (ECP)to

Knoxville (TYS)
Depart: 03/05/2026
From
$140
One-way
Basic

Fort Lauderdale (FLL)to

Knoxville (TYS)
Depart: 05/06/2026
From
$150
One-way
Basic

Indianapolis (IND)to

Knoxville (TYS)
Depart: 03/18/2026
From
$154
One-way
Basic

Jackson (JAN)to

Knoxville (TYS)
Depart: 03/11/2026
From
$154
One-way
Basic

Little Rock (LIT)to

Knoxville (TYS)
Depart: 04/15/2026
From
$154
One-way
Basic

*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

Popular flights to Knoxville on Southwest Airlines

$

*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

Discover Knoxville with Southwest Airlines

Book your next flight to Knoxville with Southwest Airlines and discover why East Tennessee is a destination filled with mountain beauty, vibrant culture, and Southern charm. Learn more about the Southwest® Experience and start planning your Knoxville getaway today.


Flying to Knoxville with Southwest Airlines

  • Enjoy easy access to East Tennessee with flights landing at Knoxville’s McGhee Tyson Airport (TYS), just minutes from downtown.
  • Arrive stress-free with Southwest’s convenient service and famously friendly hospitality.
  • With low fares and no hidden fees, Southwest makes getting to Knoxville as comfortable as the Southern charm that greets you.

Best Food & Drink in Knoxville

  • Start your day with a local favorite of biscuits smothered in sausage gravy or a made-from-scratch donut from a hometown bakery.
  • Enjoy a farm-to-table dinner at Market Square or take a short drive to Pigeon Forge for classic Southern comfort food and live dinner shows.
  • Taste Appalachian flavors inspired by the region’s mountain heritage and family recipes passed down for generations.

Find cheap flights to Knoxville

$

Baltimore/Washington (BWI)to

Knoxville (TYS)
Depart: 03/05/2026

One-way

Basic

From
$109
Seen: 6 minutes ago

Nashville (BNA)to

Knoxville (TYS)
Depart: 03/05/2026

One-way

Basic

From
$119
Seen: 7 hrs ago

Destin/Fort Walton Beach (VPS)to

Knoxville (TYS)
Depart: 03/05/2026

One-way

Basic

From
$138
Seen: 6 hrs ago

Dallas (Love Field) (DAL)to

Knoxville (TYS)
Depart: 03/05/2026

One-way

Basic

From
$139
Seen: 1 hour ago

Panama City Beach, FL (ECP)to

Knoxville (TYS)
Depart: 03/05/2026

One-way

Basic

From
$140
Seen: 13 hrs ago

Tampa (TPA)to

Knoxville (TYS)
Depart: 03/05/2026

One-way

Basic

From
$150
Seen: 16 hrs ago

Plan your trip

  • Rent a car.

    Earn Rapid Rewards® points on your next rental car.

    Rent a car

  • Book a hotel.

    Find deals for any season.

    Book a hotel

  • Plan a vacation.

    Getaways by Southwest™ offers tons of vacation packages with amazing travel deals.

    Book a vacation package

Join Rapid Rewards, our award-winning frequent flyer program1.

Sign up now

No blackout dates.

You can use your points to book any seat, on any flight, no exceptions. Any day, any time, any flight, your points are ready to take you to where you want to go.

Your points don’t expire.

You can earn points on flights and on everyday purchases with our partners, which makes getting to your destination easy. No matter when, or where, you earn them, your points won’t expire.

Free inflight WiFi thanks to T-Mobile®.2

Rapid Rewards members can go online to check email, snag a dinner reservation, or browse social media from takeoff to landing. Learn more ›

12022–2023 Freddie Awards. 2Where available. Available only on WiFi-enabled designated aircraft. Free WiFi is only for Rapid Rewards® Members.

More Southwest flights to Knoxville